Catherine O’Hara has Situs Inversus, a congenital condition where all the major visceral organs are reversed- i.e., heart on the right, liver on the left, etc.

Hrithik Roshan has two thumbs in one

Halle Berry has 6 toes on one foot

Matthew Perry lost the top portion of his middle finger in a childhood accident

Jean Claude Van Damme has a large cyst on his forehead

Kate Ground has two toes on one foot

Elizabeth Taylor was diagnosed with a genetic mutation at the FOXC2 gene at birth, resulting in a double row of eyelashes around her eyes.

Val Kilmer broke his arm while filming The Doors, when he lept from the stage and the stuntman failed to catch him

Elizabeth Berkley’s right eye is half green and half brown. The other eye is green

DJ Paul has a “baby arm”

Stephen Colbert had a tumor removed from his ear when he was 10, leaving it deformed and him deaf on that side

John Henson has a non-pigmented streak of hair on the side of his head

Paul Stanley has microtia, where the outer ears fleshy area is underdeveloped or entirely absent, he has no ear canal on the right side

Gary Burghoff has a deformed hand

Oprah has 6 toes on one foot

Shawn Marion plays with a disfigured pinkie that sticks out at an angle as a result of multiple breaks from his career

Joaquin Phoenix was born with a facial scar, which is medically known as a microform cleft

Denzel Washington broke his finger during a childhood basketball game and never had it set correctly

Andy Garcia was born with a conjoined twin attached to his shoulder

David Bowie was in a fight in his youth, resulting in an enlarged pupil in one eye

Megan Fox has brachydactlytype D BDD, clubbed thumb

Ashton Kutcher has a couple of webbed toes

Billy Corgan was born with Klippel-Trenauney syndrome KTS, he has a large port-wine stain covering most of the palm and fingers of his left hand.

Daryl Hannah lost the tip of her left hand index finger in an accident

Mark Wahlberg has a third nipple

Torry Holt calls his crooked finger a symbol of the work he’s put in

Jennifer Garner has brachymetatarsia, a condition in which one of the five long bones of the foot is shorter than the others

Seals extreme facial and scalp scarring are the result of a skin condition known as discoid lupus erythematosus DLE.

Vince Vaughn lost the tip of his right thumb in a car accident as a teenager

Mickey Rourke has gnarly fingers

George Takei claims many years ago he received shoes from a fan and that they wrecked both of his feet

[via: ebaumsworld]